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Womens Health Topics 2015

Interstitial cystitis is a clinical syndrome characterized by daytime and nighttime urinary frequency, urgency, and pelvic pain of unknown etiology. In addition, interstitial cystitis (IC) is commonly found in middle-aged women, whose characteristics are mainly the fibrosis of the bladder wall.

Through the above simple understanding, we should be aware that if want to treat the interstitial cystitis, we must first understand the causes of interstitial cystitis. Commonly known as an antidote against the disease.

All patients had normal urine, and infection was not the main cause of bladder wall fibrosis. Some scholars believe that the lymphatic obstruction caused by pelvic surgery or infection is the cause of the disease, and many patients do not have such a history. Some scholars have suggested that it may be related to endocrine factors because of the acute infection of the patients with the disease of the urinary bladder or pelvic organs, or due to the spasm of the long term of the mental impulse. There are some causes of interstitial cystitis, as follows: First, the infection. The urine culture of interstitial cystitis patients contains a few bacteria, antibiotic therapy is often ineffective. Second, inflammation is the main manifestation of interstitial cystitis. Third, mast cells and activation. Also toxic substances and hypoxia can cause damage to the bladder, then lead to interstitial cystitis.

Interstitial cystitis has no clear etiology or pathophysiology, and diagnostic criteria for the syndrome remain undefined. Despite considerable research, universally effective treatments do not exist; therapy usually consists of various supportive, behavioral and pharmacologic measures. Some people think that the Diuretic and anti-inflammatory pill is a good treatment choice.


The diagnosis of interstitial cystitis mainly depends on symptoms, physical examination, urine analysis, bladder dilation, and biopsy. Under general anesthesia, taking a cystoscopy can make diagnosis of interstitial cystitis. The appearance and volume of the bladder were normal, but when refilling the bladder after emptying it, then often can see scattered in mucosa bleeding biopsy showed edema, hyperemia, telangiectasia and blood vessels around the hemorrhage of pathological change, which also can be used to exclude some carcinoma in situ and tuberculosis lesions in the lower epidermis.

At present, the treatment effect of interstitial cystitis is unsatisfactory, 90% of the cases of conservative treatment can alleviate the symptoms, 10% of the need for surgical treatment. The usual treatments are: Behavioral therapy, which means the control of fluid intake and pelvic floor muscle training. There is drug treatment, such as sedative, glucocorticoid and anti allergy drugs, but the treatment effect is not ideal and the side effect is big, so doctors do not recommend to use . However, the Diuretic and anti-inflammatory pill can play a large role in treating the interstitial cystitis, and it has little side effect. At the same time, the pill has a good resistance to drugs.

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