Preimplantation Genetic Diagnosis (PGD)or preimplantation genetic testing is a procedure that is used to check for common abnormalities of embryo's chromosomes conceived through ICSI or IVF. These abnormalities are the major cause of embryo implantation failure that leads to miscarriages.
Screening for Genetic Disorders
Preimplantation Genetic Diagnosis can test for more than 100 genetic conditions. For many genetic conditions, there are no cures. Even if there was a treatment, there is huge risk that the child and parents would have to go through psychological trauma.In such a scenario, prevention makes more sense than waiting for a cure. This prevention is possible with screening the embryo with preimplantation genetic testing.
Saves parents the distress
Preimplantation genetic diagnosis is done before the embryo is implanted in the womb and a pregnancy is established as opposed to prenatal diagnostic testing. This saves the parents from the decision to terminate an affected pregnancy. Couples canavoid the psychological trauma associated with diagnosis, particularly if late in an established pregnancy, as well as the risk of miscarriage, with preimplantation genetic testing.
Alternative to pregnancytermination
If prenatal testing reveals a genetic abnormality later in the pregnancy, the pregnancy has to be terminated. This can be a traumatic decision. Since Preimplantation Genetic Diagnosis is performed before pregnancy begins, such difficult experiences can be avoided. The choice of going for Preimplantation Genetic Testing is quite personal and complicated. It is advisable to consult your fertility specialist at the best fertility clinic in UAE, PRC Dubai, before making a final decision.
Opportunity to have a baby unaffected by a family genetic condition
Couples, with a genetic condition running in either family, often chose adoption or surrogacy or not to have children, to avoid the risk of an affected child. Preimplantation Genetic Diagnosis now allows such couples the opportunity to have a healthy child.
Reducing risk for high risk groups
Preimplantation genetic testing reduces the risk of pregnancy termination or failure in certain groups who are vulnerable to chromosomal abnormalities. Dubai fertility doctor may recommend you go for PGD at PRC Dubai if you belong to one of the following groups:
- Women with advanced female age (38 or older) undergoing In Vitro Fertilization treatment
- Women of any age with several unsuccessful IVF cycles
- Women who have had recurrent miscarriages
- Men with sperms that are at a high risk for chromosome problems
- Coupleswith family history of chromosome problems
- Couples who are both carriers for a recessive genetic disease
The Dubai fertility specialist will discuss your PGD results with you and only normal embryos will be used for IVF cycles. PGD allows the doctor to use genetically normal embryos for transfer, increasing the chances of IVF success. When all chromosomes are evaluated, and assessed as normal, the chances of pregnancy are about 85-90%.